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Octobre 2016

 

Lundi
03 / 10 / 2016
11h00
" Pathophysiology of Vitiligo 4-(4-hydroroxyphenyl)-2-butanol (rhododendrol) induced leukoderma as a new model of vitiligo"
 

   Ichiro KATAYAMA (Department of Dermatology Course of Integrated Medicine Graduate School of Medicine, Osaka University, Japan)  

   Hôte: Jean-François Nicolas 

 

   Amphi Pasteur CERVI

Lundi
03 / 10 / 2016
11h00
"Growth and survival of Brucella abortus in culture and in infection"

 

Xavier de BOLLE  (Université de Namur, Belgium)

invited by S. Salcedo

 

IBCP Confernce Room level -1

Vendredi
07 / 10 / 2016
11h00
"The Fbox protein CG6758 regulates LaminB to suppress Xbp1-induced cell death in the Drosophila eye"

 

   Pedro DOMINGOS (ITQB, Oeiras, Portugal)        

 

   Salle CO23 du CBP rez-de-chaussée LR6

Vendredi
07 / 10 / 2016
15h30
"Analysis of Alzheimer risk factors and Tau toxicity in Drosophila"

 

    Pierre DOURLEN (Insitut Pasteur, Lille)  

 

    Salle CO23 du CBP rez-de-chaussée LR6

Lundi
10 / 10 / 2016
11h00
"Neuroendocrine polypharmacy targeting obesity and diabetes”
 

    Matthias TSCHÖP (Helmholtz Centre, Munich)      

 

    Salle des Thèses Chantal Rabourdin-Combe

Lundi
10 / 10 / 2016
11h00
"Macromolecular interactions of the bacterial division FtsZ protein - from biochemistry and crowding to reconstructing minimal divisomes in the test tube"

 

German RIVAS  CABALLERO ( Department of Cellular and Molecular Biology; Centro de Investigaciones Biológicas, Spanish National Research Council (CSIC), Madrid, Spain)

invited by C. Grangeasse

IBCP Confernce Room level -1

Mardi
11 / 10 / 2016
11h00
"Multipurpose DARPin Binders for Innovative Applications - How to Identify the Binders best suited for Challenging Tasks"

 

Dr. Jonas SCHAEFER (High-Throughput Binder Selection Facility Department of Biochemistry , University of Zurich)            

Invited by Sandrine Vadon-Le Goff 

Designed ankyrin repeat proteins (DARPins) can recognize targets with specificities and affinities that equal or surpass those of antibodies, but because of their robustness and extreme stability, they allow amultitude of more advanced formats and applications.  In research, they have been established as intracellular, real-time sensors of protein conformations and as crystallization chaperones. For future therapies, DARPins have been developed by advanced, structure-based protein engineering to selectively induce apoptosis in tumors by uncoupling surface receptors from their signaling cascades. They have also been used successfully for retargeting viruses. In ongoing clinical trials, DARPins have shown good safety and efficacy in macular degeneration diseases.These developments all ultimately exploit the high stability, solubility, and aggregation resistance of these molecules, permitting a wide range of conjugates and fusions to be produced and purified.

 

IBCP Confernce Room level -1                                                                                                            

Lundi
24 / 10 / 2016
11h00
"Transmitting an epigenetic “memory of germline” across generations and through development"

 

Susan STROME  (Distinguished Professor of Molecular, Cell and Developmental Biology at UC Santa Cruz)  

Susan is a leading expert in the field.  Using a combination of elegant genetic and genomic approaches she has described several examples of epigenetic inheritance, as well as reprogramming of germ cells.
Her latest publication include
Gaydos, L., W. Wang, and S. Strome.  2014.  H3K27me and PRC2 transmit a memory of repression across generations and during development.  Science 345: 1515-1518.
Updike, D., A. Knutson, T. Egelhofer, A. Campbell, and S. Strome.  2014.  Germ-granule components prevent somatic development in the C. elegans germline.  Current Biology 24: 970-975.
Gaydos, L., A. Rechtsteiner, T. Egelhofer, C. Carroll, and S. Strome.  2012.  Antagonism between MES-4 and Polycomb Repressive Complex 2 promotes appropriate gene expression in C. elegans germ cells.  Cell Reports 2: 1169-1177

     

1 place de l'Ecole

 

 
16-18 /11 / 2016
9h00

A VENIR

International conference

https://lyonsysbio2015.sciencesconf.org/?lang=en

Contact: François Briat   francois.briat@ens-lyon.fr

LyonSysBio is the yearly international conference organized by BioSyL (http://lyonsysbio2015.sciencesconf.org/?lang=en), the Systems Biology Alliance of Lyon.
Its goal is to promote exchanges between scientists from different fields (biology, mathematics, computer sciences, physics, social sciences…) interested in the analysis of the wealth of data generated by modern biology, as well as the construction of the necessary modeling tools to gain system level thoughtful insights.
In 2015, the conference will be held from the 18th to the 20th of November in Lyon. It will be dedicated to discussions around the 4 following themes: systems immunology, cell differentiation, a systems view on genotype-phenotype relationship and microbiological systems biology. Keynote lectures will be delivered by the following speakers:
Gregoire Altan-Bonnet (MSK cancer center, New-York)
Becca Asquith (Imperial College, London)
Chris Bakal (Institute of cancer research, London)
Sckjoon Jun (University of California, San Diego)
James Locke (University of Cambridge)
John Marioni (European Bioinformatics Institute, Cambridge)
Carsten Peterson (Computational Biology & Biological Physics, Lund University, Sweden)
Andreas Wagner (IEU, University of Zurich)

 

 

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