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Microscope biphoton Bruker Ultima

A two-photon microscope for in vivo imaging is now available

A new two-photon microscope available to the scientific community for in vivo imaging

This equipment features a dual-output Spectra Physics InSight femtosecond laser (fixed at 1040 nm and tunable from 680 to 1300 nm), offering great excitation flexibility for a wide range of fluorophores.

It is also equipped with three high-sensitivity detectors, ensuring optimal detection of even the weakest signals, as well as a controlled-environment chamber suitable for imaging small live animals under stable physiological conditions.

This new instrument opens exciting prospects for projects requiring high spatiotemporal resolution and dynamic observation of biological processes.

It is located at the Lyon-Est Faculty of Medicine (8, avenue Rockefeller – 69008 Lyon), within the ANIPHY platform facilities, and can be booked via the CIQLE platform : ici.  

 

For any inquiries, please contact : Denis Ressnikoff (denis.ressnikoff@univ-lyon1.fr) and Emmanuelle Girard (emmanuelle.girard@univ-lyon1.fr). 

 

 

Microscope biphoton Bruker Ultima : microscope à optique non-linéaire conçu pour l'imagerie in-vivo en profondeur (500µm, voire au-delà)

 

Morphology of microglia expressing GFP during wake (magenta) and sleep (cyan) episodes in vivo (x20)

Crédit :INMG-MELiS - équipe Honnorat - Image : Kassandre Combet

Cerebellar cortex GCaMp8s

Crédit : INMG-PGNM - équipe Puccio - Image : Federica Pilotto

Dendrite from corticol neuron expressing CFP in vivo (x20) 

Crédit : INMG-MELiS - équipe Honnorat - Image : Kassandre Combet. 

 

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