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Janvier 2025

Mardi
07/01/2025

11h00

Seminar room IBCP

Séminaire externe

“Dispositifs médicaux pour restaurer, régénérer et remplacer les tissus dentaires”

 

 

 

Nina ATTIK 
(équipe biomatériaux LMI UCBL-CNRS UMR5615) 
Invited by M. Ducret

Mardi
14/01/2025

14h00

Amphi Pasteur

Séminaire externe

“ Yersinia pestis, from fleas to rodents ”

     
Florent SEBANNE (Institut Pasteur de Lille) 
Hôte : T. Henry
 
Yersinia pestis is the agent responsible for plague, a fatal disease in wildlife that sometimes affects humans. The presentation will focus on the physiological and molecular mechanisms that lead to the production of a transmissible infection of Y. pestis by fleas and the consequences of this transmission in mammals.                                                                                                                              

Vendredi
17/01/2024

11h00
SDT CRC
 

Séminaire externe

“ Regulation and orchestration of DNA repair mechanisms within the nuclear space ”

 

  

Pierre CARRON (IBS Grenoble) 
Hôte : A. Piazza                                                                                                                                                                                                                                                                                                            

Mercredi
22/01/2025

15h00
SDT CRC
 

Séminaire Externe

“ Innate Immunity in Alzheimer’s disease ”
Pr. Michael HENEKA (Luxembourg Centre for Systems Biomedicine (LCSB) 
Hôte : B. Py
 
Michael Heneka is a board-certified neurologist and clinician-scientist with over 25 years of experience in studying neurodegenerative diseases at experimental, preclinical and clinical levels. He has a long-standing interest in immunology and neuroscience. While the main focus of his work is related to dementia and Alzheimer’s disease, he has also been working on Amyotrophic Lateral Sclerosis and Parkinson’s disease.
 

 

Lundi
27/01/2025

11h00

Salle Condorcet

Séminaire Externe

 “TBC”
Laura MOODY (University of Oxford, UK)  
Hôte : Charlotte Kirchhelle                   

Lundi
27/01/2025

11h00

Amphi Pasteur
 

Séminaire Externe

“ Bacterial contractile injection systems: from mechanism to engineering ”

      
Pr. Martin PILHOFER (ETH Zurich)  
Hôte : T. Henry
 
Contractile injection systems (CISs) are macromolecular machines that mediate microbial cell-cell interactions. The Pilhofer Lab investigates the different modes of action by which CISs function. Based on the gained mechanistic insights, we attempt to engineer CISs for biomedical applications.                                                                                                   

 

Mardi
28/01/2025

11h00

Seminar room IBCP
 

Séminaire externe

“WhiteFox, an alternative to Biacore ?”
      

 

Mardi
28/01/2025

11h00
 
SDT CRC
 

Séminaire externe

“ Exploring immunity on the functional level – stories of effectors measured on the single-cell level ”

 
Pr. Klaus EYER  (Aarhus University, Denmark)
Hôte :N. Personnic
 
The immune system's complexity lies not only in its diverse cell types but also in the distinct and dynamic functions performed by individual cells, and a deep exploration of how individual cells function and interact to drive complex immune responses can provide new insights into immunity. Traditional bulk analyses often obscure the heterogeneity of immune responses, whereas single-cell technologies now enable precise measurement of effector functions such as cytokine production and antibody secretion. These methods have revealed the multifunctionality of immune cells, where individual cells can perform multiple tasks simultaneously or sequentially. Exploring effector functions at the single-cell level provides critical insights into immune regulation, disease mechanisms, and potential therapeutic strategies, offering a deeper understanding of immunity.
This talk will highlight the technologies that we have developed to do so, and moreover, how a detailed picture of humoral and adaptive immunity can provide novel insights into the responses following vaccination and autoimmune disease. Lastly, these measures can be exploited to screen for rare, functional, and (cross-)specific antibodies. Particularly, assaying antibody specificity on the individual antibody level might prove interesting for finding therapeutic candidates against pathogens.

 
 

 

 
   
   
   
                                                                                               
   
 
                                                                                                                                                        
 
 
 
 
 
 
 
    
   
   

 

 

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